API Obeticholic acid CAS 459789-99-2 no biliary cholangitis

API Obeticholic acid CAS 459789-99-2 no ka cholangitis biliary

ʻO ka wehewehe pōkole:

Hoʻohana ʻia ka ʻakika Obeticholic wale nō a i ʻole ka hui pū ʻana no kekahi maʻi ate (primary biliary cholangitis-PBC).

Hoʻokaʻaʻike: Erica Zheng

Email: erica@zhuoerchem.com

Kelepona: +86 21 2097 0332

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Skype: slhyzy

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

wehewehe

Hoʻohana ʻia ka ʻakika Obeticholic wale nō a i ʻole ka hui pū ʻana no kekahi maʻi ate (primary biliary cholangitis-PBC).

Hōʻike:

inoa mea kūʻai	Obeticholic Acid
Inoa Kimia	6-Ethylchenodeoxycholic acid
Inoa ʻē aʻe	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic Acid -ECDCA)
Helu CAS	459789-99-2
ʻĀpana Molekala	C26H44O4
Kaumaha Formula	420.63
Ka nana aku	Pauda keʻokeʻo
Hoʻāʻo	99.0% min
ʻO ka mānoanoa	1.091 g/cm3
Lae hehee	108-110 °C
Lae paila	562.9±25.0 °C
Pūʻolo	20kg / ʻeke / pahu, 25kg / ʻeke / pahu, a i ʻole e like me kou makemake
Waihona	E mālama i ka pahu i paʻa paʻa i kahi maloʻo a maloʻo.Mai hōʻike i ka lā pololei.
COA & MSDS	Loaʻa

Hoʻohana

ʻO ka ʻakika Obeticholic he waikawa dihydroxy-5beta-cholanic ʻo ia ka chenodeoxycholic acid e lawe ana i kahi mea ethyl substituent ma ke kūlana 6alpha.He waikawa bile semi-synthetic e hana ana ma ke ʻano he farnesoid X receptor agonist a hoʻohana ʻia no ka mālama ʻana i ka cholangitis biliary mua.He kuleana kona ma ke ʻano he farnesoid X receptor agonist a he hepatoprotective agent.He dihydroxy-5beta-cholanic acid, he 3alpha-hydroxy steroid a me ka 7alpha-hydroxy steroid.Loaʻa ia mai kahi chenodeoxycholic acid.
ʻO ka waika Obeticholic (OCA) he waika bile i hoʻololi ʻia a me ka agonist ikaika o ka farnesoid X nuclear receptor (FXR) i hoʻohana ʻia e mālama i nā maʻi ate me ka cholangitis biliary mua.